Mouse NOV (Nephroblastoma Overexpressed Gene) ELISA Kit
Product Sizes
24 tests
£143.00
E-EL-M3115-24TESTS
48 tests
£295.00
E-EL-M3115-48TESTS
96 tests
£356.00
E-EL-M3115-96TESTS
About this Product
- SKU:
- E-EL-M3115
- Additional Names:
- CCN3,IGFBP9,NOVH,IBP-9,Insulin-like growth factor-binding protein 9,Protein NOV homolog
- Application:
- ELISA
- Extra Details:
- NOV (CCN3) is a member of the CCN family of secreted,cysteine-rich regulatory proteins that share four conserved modules which confer distinct biological activities. These modules include an insulin-like growth factor binding domain,a von Willebrand type C domain,thrombospondin-1 domain,and a C-terminal cysteine knot domain. It is widely expressed developmentally,especially in the muscle,endothelium,nervous system,adrenal cortex,and chondrocytes. NOV (CCN3) acts through the Notch and BMP signaling pathways to modulate self-renewal and maturation of a number of cell lineages including hematopoietic,osteogenic,and chondrogenic lineages. NOV (CCN3) is also a putative ligand for integrin receptors and is tightly associated with the extracellular matrix. Its interaction with integrins alpha v beta 3 and alpha 5 beta 1 mediates endothelial cell adhesion induces chemotaxis and promotes angiogenesis. The elevated expression of NOV (CCN3) is associated with certain tumors such as Wilm's tumor and most nephroblastomas.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Range:
- 125-8000 pg/mL
- Reactivities:
- Mouse
- Sensitivity:
- 74.32 pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:p-mouse_nov_(nephroblastoma_overexpressed_gene)_elisa_kit-e_el_m3115
