Mouse ACE2 (Angiotensin I Converting Enzyme 2) ELISA Kit
Product Sizes
24 tests
£143.00
E-EL-M3113-24TESTS
48 tests
£295.00
E-EL-M3113-48TESTS
96 tests
£356.00
E-EL-M3113-96TESTS
About this Product
- SKU:
- E-EL-M3113
- Additional Names:
- ACEH,ACEII
- Application:
- ELISA
- Extra Details:
- ACE2 is a member of the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases. It catalyzes the cleavage of the decapeptide angiotensin I into angiotensin-(1-9) and angiotensin II (potent vasoconstrictor) into the vasodilator angiotensin-(1-7). ACE2 is a type I membrane protein that functions as a carboxypeptidase. It cleaves between a proline and a single hydrophobic/basic residue from the COOH-terminus of its substrates. ACE2 is a zinc metalloprotease with considerable homology to angiotensin I-converting enzyme (ACE),both enzymes contain the typical HEXXH zinc-binding motif,ACE has two catalytic sites and ACE2 has only one,and ACE2 is not inhibited by ACE inhibitors captopril,lisinopril,and enalaprilat. Studies in mice showed that disruption of ACE2 induced a severe cardiac contractility defect and increased angiotensin II levels in heart. Human ACE2 has been identified as the receptor for SARS (severe acute respiratory syndrome)-coronavirus.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Range:
- 0.78-50 ng/mL
- Reactivities:
- Mouse
- Sensitivity:
- 0.47 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:p-mouse_ace2_(angiotensin_i_converting_enzyme_2)_elisa_kit-e_el_m3113
