Mouse Lptn/XCL1(Lymphotactin) ELISA Kit
Product Sizes
24 tests
£143.00
E-EL-M0763-24TESTS
48 tests
£388.00
E-EL-M0763-48TESTS
96 tests
£473.00
E-EL-M0763-96TESTS
About this Product
- SKU:
- E-EL-M0763
- Additional Names:
- SCYC1,LTN,ATAC,SCM-1a,SCM-1,Chemokine(C motif) ligand,XCL1,Lptn
- Application:
- ELISA
- Extra Details:
- XCL1, also known as lymphotactin, is an inflammatory chemokine secreted by T cells and natural killer (NK) cells. The XCL1-XCR1 axis has been shown to play an important role in the dendritic cell mediated cytotoxic immune response and in the formation of self-tolerance mechanisms through the development of regulatory T cells within the thymus. XCL1 also acts as a conformation-dependent inhibitor of HIV-1. Unlike other chemokines, XCL1 conformation interchanges between conserved chemokine folds and an unrelated dimeric structure under physiological conditions. The XCL1 monomer binds XCR1 with a high affinity, whereas the dimer form binds glycosaminoglycans (GAGs) with a high affinity, but fails to activate XCR1.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Range:
- 62.5-4000 pg/mL
- Reactivities:
- Mouse
- Sensitivity:
- 37.5 pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:xcl1(lymphotactin)_elisa_kit-e_el_m0763
