Human SLAMF2 (Signaling Lymphocytic Activation Molecule Family, Member 2) ELISA Kit
Product Sizes
24 tests
£134.00
E-EL-H6315-24TESTS
48 tests
£311.00
E-EL-H6315-48TESTS
96 tests
£377.00
E-EL-H6315-96TESTS
About this Product
- SKU:
- E-EL-H6315
- Additional Names:
- CD48 antigen,B-lymphocyte activation marker BLAST-1,BCM1 surface antigen,Leukocyte antigen MEM-102,SLAM family member 2,SLAMF2,Signaling lymphocytic activation molecule 2
- Application:
- ELISA
- Extra Details:
- Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein interacts via its N-terminal immunoglobulin domain with cell surface receptors (e.g., CD244/2B4, CD2) to regulate immune cell function and activation. It participates in T-cell signaling transduction by associating with CD2, efficiently recruiting Src family protein kinase LCK and LAT to the TCR/CD3 complex, thereby promoting LCK phosphorylation and activation. Additionally, it induces phosphorylation of the cytoplasmic immunoreceptor tyrosine switch motifs (ITSMs) of CD244, initiating signaling events that drive immunological synapse formation and directed release of cytolytic granules (containing perforin and granzymes) by T-lymphocytes and NK-cells.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Range:
- 0.16-10 ng/mL
- Reactivities:
- Human
- Sensitivity:
- 0.09 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:p-human_slamf2_(signaling_lymphocytic_activation_molecule_family,_member_2)_elisa_kit-e_el_h6315
