Anti-Human CD8a-FITC/CD4-PE/CD3-PE/Cyanine7/CD45-PerCP Cocktail
Product Sizes
20 tests
£166.00
E-AB-FC0010-20TESTS
100 tests
£305.00
E-AB-FC0010-100TESTS
2 x 100 tests
£459.00
E-AB-FC0010-2X100TESTS
About this Product
- SKU:
- E-AB-FC0010
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- OKT-8;RPA-T4;OKT-3;HI30
- Clonality:
- Monoclonal
- Conjugate:
- FITC, PerCP, R-PE, R-PE-Cyanine 7
- Concentration:
- 5 ul/test
- Extra Details:
- This product is a FCM antibody cocktail made up of FITC Anti-Human CD8a Antibody [Clone: OKT-8] (Mouse IgG2a, K Kappa), PE Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, K Kappa), PE/Cyanine7 Anti-Human CD3 Antibody [Clone: OKT-3] (Mouse IgG2a, K Kappa) and PerCP Anti-Human CD45 Antibody [Clone: HI30] (Mouse IgG1, K Kappa).; CD8 is mainly expressed on cytotoxic T cells and also some subpopulations of NK cells. CD8 forms dimer function. In most cells, CD8 is a heterodimer consisting of CD8a and CD8b, but in NK cells nearly all CD8 is homodimer of CD8a. CD8a can form co-receptor with MHC-I restricted TCR to promote T cell antigen recognition and activation.; CD4 is also called Leu-3 or T4. It's a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection.; CD3 is a heterotetrameric protein consisting of a CD3G Gamma, a CDD Delta and 2 CD3E Epsilon. It forms complex with TCR. OKT-3 recognize human CD3E Epsilon. Human CD3 is expressed on the surface of T cells and NKT cells.; CD45 is a single-chain type I transmembrane glycoprotein. Except for erythrocytes and platelets, CD45 is expressed on nearly all of the hematopoietic cells with high level. It is a common marker for blood leukocytes. CD45 is a receptor type protein tyrosine phophatase and plays essential roles in B cell and T cells signaling.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Arrays
- Manufacturer's Data Sheet:cd45_percp_cocktail-e_ab_fc0010
