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Antibodies

Anti-Human CD3-FITC/CD4-PE/CD45-PerCP-Cyanine5.5 Cocktail

Product Sizes
20 tests
£209.00
E-AB-FC0003-20TESTS
100 tests
£348.00
E-AB-FC0003-100TESTS
2 x 100 tests
£509.00
E-AB-FC0003-2X100TESTS
About this Product
SKU:
E-AB-FC0003
Application:
Flow Cytometry
Buffer:
pbs
Clone:
OKT-3,RPA-T4,HI30
Conjugate:
FITC, PerCP-Cyanine 5.5, R-PE
Extra Details:
This product is a FCM antibody cocktail made up of FITC Anti-Human CD3 Antibody [Clone: OKT-3] (Mouse IgG2a, K Kappa),PE Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, K Kappa) and PerCP/Cyanine5.5 Anti-Human CD45 Antibody [Clone: HI30] (Mouse IgG1, K Kappa). CD3 is a heterotetrameric protein consisting of a CD3G Gamma, a CDD Delta and 2 CD3E Epsilon. It forms complex with TCR. OKT-3 recognize human CD3E Epsilon. Human CD3 is expressed on the surface of T cells and NKT cells. CD4 is also called Leu-3 or T4. It's a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection. CD45 is a single-chain type I transmembrane glycoprotein. Except for erythrocytes and platelets, CD45 is expressed on nearly all of the hematopoietic cells with high level. It is a common marker for blood leukocytes. CD45 is a receptor type protein tyrosine phophatase and plays essential roles in B cell and T cells signaling.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Antibody Duo