Anti-Human CD3-APC/CD4-FITC/CD8a-PerCP-Cyanine5.5 Cocktail
Product Sizes
20 tests
£220.00
E-AB-FC0002-20TESTS
100 tests
£369.00
E-AB-FC0002-100TESTS
2 x 100 tests
£545.00
E-AB-FC0002-2X100TESTS
About this Product
- SKU:
- E-AB-FC0002
- Application:
- Flow Cytometry
- Buffer:
- pbs
- Clone:
- OKT-3,RPA-T4,OKT-8
- Conjugate:
- APC, FITC, PerCP-Cyanine 5.5
- Extra Details:
- This product is a FCM antibody cocktail made up of APC Anti-Human CD3 Antibody [Clone: OKT-3] (Mouse IgG2a, K Kappa), FITC Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, K Kappa) and PerCP/Cyanine5.5 Anti-Human CD8a Antibody [Clone: OKT-8] (Mouse IgG2a, K Kappa). CD3 is a heterotetrameric protein consisting of a CD3G Gamma, a CDD Delta and 2 CD3E Epsilon. It forms complex with TCR. OKT-3 recognize human CD3E Epsilon. Human CD3 is expressed on the surface of T cells and NKT cells. CD4 is also called Leu-3 or T4. It's a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection. CD8 is mainly expressed on cytotoxic T cells and also some subpopulations of NK cells. CD8 forms dimer function. In most cells, CD8 is a heterodimer consisting of CD8a and CD8b, but in NK cells nearly all CD8 is homodimer of CD8a. CD8a can form co-receptor with MHC-I restricted TCR to promote T cell antigen recognition and activation.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Antibody Duo
- Manufacturer's Data Sheet:p-anti_human_cd3_apc_cd4_fitc_cd8a_percp_cyanine5.5_okt_3_rpa_t4_okt_8_-376611.html