APC Anti-Human CD158b/j Antibody[DX27]
Product Sizes
20 tests
£128.00
E-AB-F1381E-20TESTS
100 tests
£235.00
E-AB-F1381E-100TESTS
2 x 100 tests
£367.00
E-AB-F1381E-2X100TESTS
About this Product
- SKU:
- E-AB-F1381E
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- DX27
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 5 ul/test
- Extra Details:
- CD158b is expressed on natural killer cells and a subset of T cells. It is a member of the immunoglobulin superfamily containing two immunoglobulin C2-type domains. Both variants and alternative isoforms of CD158b have been reported. The interaction of CD158b with specific HLA-C antigens on a target cell (HLA-Cw1, HLA-Cw3, HLA-Cw7 alleles, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK cell and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease.
- Host:
- Mouse
- Immunogen:
- CD158b/j
- Isotype:
- IgG2a, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:SKCVm5
