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Antibodies

Elab Fluor[R] 647 Anti-Human CD244 Antibody[C1.7]

Product Sizes
20 tests
£143.00
E-AB-F1374M-20TESTS
100 tests
£270.00
E-AB-F1374M-100TESTS
2 x 100 tests
£378.00
E-AB-F1374M-2X100TESTS
About this Product
SKU:
E-AB-F1374M
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
C1.7
Clonality:
Monoclonal
Conjugate:
Elab Fluor® 647
Concentration:
5 ul/test
Extra Details:
CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and G Gamma/D Delta T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
Host:
Mouse
Immunogen:
CD244
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody