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Antibodies

Elab Fluor[R] 700 Anti-Mouse CD172a/SIRPA Alpha Antibody[P84]

Product Sizes
50 tests
£126.00
E-AB-F1286M1-50TESTS
100 tests
£174.00
E-AB-F1286M1-100TESTS
2 x 100 tests
£262.00
E-AB-F1286M1-2X100TESTS
About this Product
SKU:
E-AB-F1286M1
Additional Names:
BIT;CD172 antigen-like family member A;P84;PTPNS1;SHPS-1;SIRPA Alpha
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
P84
Clonality:
Monoclonal
Conjugate:
Elab Fluor® 700
Extra Details:
CD172a, also known as SIRPA Alpha, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPA Alpha ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
Host:
Rat
Immunogen:
CD172a
Isotype:
IgG1, kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody