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Antibodies

Purified Anti-Mouse CD172a Antibody[P84]

Product Sizes
25 ug
£66.00
E-AB-F1286A-25UG
100 ug
£89.00
E-AB-F1286A-100UG
1 mg
£165.00
E-AB-F1286A-1MG
5 mg
£467.00
E-AB-F1286A-5MG
25 mg
£1438.00
E-AB-F1286A-25MG
50 mg
£2132.00
E-AB-F1286A-50MG
100 mg
£2980.00
E-AB-F1286A-100MG
About this Product
SKU:
E-AB-F1286A
Additional Names:
Myd;SHPS;Ptpns;Bit;Myd1;Ptpns1;Shps1;Sirp;Sirpa; SIRP&beta-1-1;SIRPαSIRPβAI835480;CD172a;P84;SHP-1;SHPS-1
Application:
Flow Cytometry
Buffer:
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
translate.label.attr.clone:
P84
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization. Receptor for THBS1. Interaction with THBS1 stimulates phosphorylation of SIRPA. In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production.
Host:
Rat
Immunogen:
CD172a|Recombinant Mouse CD172a protein
Isotype:
IgG1, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:8pHta1