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Antibodies

Purified Anti-Human CD86 Antibody[IT2.2], Functional Grade

Product Sizes
100 ug
£89.00
E-AB-F12690-100UG
1 mg
£171.00
E-AB-F12690-1MG
5 mg
£490.00
E-AB-F12690-5MG
25 mg
£1515.00
E-AB-F12690-25MG
50 mg
£2247.00
E-AB-F12690-50MG
100 mg
£3211.00
E-AB-F12690-100MG
About this Product
SKU:
E-AB-F12690
Additional Names:
LAB,ETC,FUN,CTLA-4 Counter-Receptor B,Early T-cell costimulatory molecule,CD28LG,B7-2,B7.2,B70,CD28LG2,LAB72,CD86,Activation B7-2 antigen,BU63,CTLA-4 Counter-Receptor B7.2,Early T-cell costimulatory molecule 1,ETC-1,FUN-1,T-lymphocyte activation antigen CD86, B7-2,Activation B7-2 antigen 3,B7 2,B72 antigen,B-lymphocyte activation antigen B7-2,B-lymphocyte activation antigen B7-2 2,CD28 antigen ligand 2,CD28 antigen ligand 2 2,Cd28l2,CD86 antigen,CD86 molecule,CLS1,CTLA-4 counter-receptor B7.2 2,FUN 1,Ly58,Ly-58,MB7,MB7-2,Membrane glycoprotein,MGC34413,TS/A-2
Application:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
IT2.2
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Mouse
Immunogen:
Recombinant Human CD86 protein
Isotype:
IgG2b, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Human peripheral blood monocytes cell were stained with 0.2 ug Purified Anti-Human CD86 Antibody[IT2.2], Functional Grade (Right) and 0.2 ug Mouse IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood monocytes were stained with 0.2 ug Purified Anti-Human CD33 Antibody[P67.6] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD14 FITC-conjugated Monoclonal Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD55 Antibody[HI55a] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by APC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood monocytes were stained with 0.2 ug Purified Anti-Human CD33 Antibody[HIM3-4] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD14 FITC-conjugated Monoclonal Antibody.
Human peripheral blood platelets were stained with 0.2 ug Purified Anti-Human CD41 Antibody[10E5-F0061] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.