APC Anti-Mouse CD51 Antibody[RMV-7]
Product Sizes
50 tests
£101.00
E-AB-F1235E-50TESTS
100 tests
£128.00
E-AB-F1235E-100TESTS
2 x 100 tests
£174.00
E-AB-F1235E-2X100TESTS
About this Product
- SKU:
- E-AB-F1235E
- Additional Names:
- ITGAV;Integrin alpha-V;Integrin A AlphaV chain;Vitronectin Receptor;A AlphaV integrin
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- RMV-7
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 5 ul/test
- Extra Details:
- CD51 is a 140 kD protein, also known as A AlphaV integrin, vitronectin receptor, and integrin A AlphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins B Beta1, B Beta3, B Beta5 or B Beta6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The A Alphavintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
- Host:
- Rat
- Immunogen:
- CD51
- Isotype:
- IgG1, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-apc_anti_mouse_cd51_antibody[rmv_7]-e_ab_f1235e
