Purified Anti-Mouse CD51 Antibody[RMV-7], Functional Grade
Product Sizes
100 ug
£89.00
E-AB-F12350-100UG
1 mg
£171.00
E-AB-F12350-1MG
5 mg
£490.00
E-AB-F12350-5MG
25 mg
£1515.00
E-AB-F12350-25MG
50 mg
£2247.00
E-AB-F12350-50MG
100 mg
£3211.00
E-AB-F12350-100MG
About this Product
- SKU:
- E-AB-F12350
- Additional Names:
- Integrin alpha-V,Integrin A AlphaV chain,Vitronectin Receptor,A AlphaV integrin,Itgav,vitronectin R,integrin &,alpha-V-V
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- RMV-7
- Clonality:
- Monoclonal
- Concentration:
- >= 1 mg/ml
- Extra Details:
- CD51 is a 140 kD protein, also known as A AlphaV integrin, vitronectin receptor, and integrin A AlphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins B Beta1, B Beta3, B Beta5 or B Beta6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The A Alphav integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Host:
- Rat
- Immunogen:
- Recombinant MouseCD51 protein
- Isotype:
- IgG1, kappa
- Purification:
- protein a/g purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-purified_anti_mouse_cd51_antibody[rmv_7],_functional_grade-e_ab_f12350
