APC Anti-Mouse CD200/OX2 Antibody[OX-90]
Product Sizes
25 ug
£115.00
E-AB-F1234UE-25UG
100 ug
£235.00
E-AB-F1234UE-100UG
About this Product
- SKU:
- E-AB-F1234UE
- Additional Names:
- MRC;OX-2;OX-2 membrane glycoprotein
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- OX-90
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 0.2 mg/ml
- Extra Details:
- CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons); but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R). The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.
- Host:
- Rat
- Immunogen:
- CD200/OX2
- Isotype:
- IgG2a, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ox2_antibody[ox_90]-e_ab_f1234ue
