APC Anti-Human CD279/PD-1 Antibody[EH12.2H7]
Product Sizes
20 tests
£209.00
E-AB-F1229E-20TESTS
100 tests
£300.00
E-AB-F1229E-100TESTS
2 x 100 tests
£396.00
E-AB-F1229E-2X100TESTS
About this Product
- SKU:
- E-AB-F1229E
- Additional Names:
- PDCD1,PD1,Protein PD-1,hPD-1
- Application:
- Flow Cytometry
- Buffer:
- pbs
- Clone:
- EH12.2H7
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
- Host:
- Mouse
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-apc_anti_human_cd279_pd_1_antibody_eh12.2h7_e_ab_f1229e-376701.html