Purified Anti-Human CD279/PD-1 Antibody[J110]
Product Sizes
25 ug
£66.00
E-AB-F1213A-25UG
100 ug
£89.00
E-AB-F1213A-100UG
1 mg
£165.00
E-AB-F1213A-1MG
5 mg
£467.00
E-AB-F1213A-5MG
25 mg
£1438.00
E-AB-F1213A-25MG
50 mg
£2132.00
E-AB-F1213A-50MG
100 mg
£2980.00
E-AB-F1213A-100MG
About this Product
- SKU:
- E-AB-F1213A
- Additional Names:
- PD1;PDCD1;Protein PD-1;hPD-1
- Application:
- Flow Cytometry
- Buffer:
- Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
- translate.label.attr.clone:
- J110
- Clonality:
- Monoclonal
- Concentration:
- >= 1 mg/ml
- Extra Details:
- Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
- Host:
- Mouse
- Immunogen:
- CD279/PD-1
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:Oyrr9O
