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Antibodies

AF/LE Purified Anti-Human CD279/PD-1 Antibody[J110]

Product Sizes
25 ug
£66.00
E-AB-F12130-25UG
100 ug
£89.00
E-AB-F12130-100UG
1 mg
£171.00
E-AB-F12130-1MG
5 mg
£490.00
E-AB-F12130-5MG
25 mg
£1515.00
E-AB-F12130-25MG
50 mg
£2247.00
E-AB-F12130-50MG
100 mg
£3211.00
E-AB-F12130-100MG
About this Product
SKU:
E-AB-F12130
Additional Names:
PD1;PDCD1;Protein PD-1;hPD-1
Application:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
J110
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Host:
Mouse
Immunogen:
CD279/PD-1
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:KGmfT8
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD45 Antibody[30-F11] (Right) and 0.2 ug Rat IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor®647-conjugated Goat Anti-Rat IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD45RO Antibody[UCHL1](Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control(Left), followed by APC-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD45RA FITC-conjugated Monoclonal Antibody and anti-Human CD3 PerCP-conjugated Monoclonal Antibody. Data shown were from CD3+ population.
Human peripheral blood lymphocytes were activated for 6 hour with PMA+ ionomycin, then stained with 0.2 ug Purified Anti-Human CD69 Antibody[FN50] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control(Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood were stained with 0.2 ug Purified Anti-Human CD45 Antibody[HI30] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD45 Antibody[30-F11] (Right) and 0.2 ug Rat IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor®647-conjugated Goat Anti-Rat IgG Secondary Antibody.