Purified Anti-Human IL-21 Antibody[3A3-N2]
Product Sizes
25 ug
£99.00
E-AB-F1202A-25UG
100 ug
£169.00
E-AB-F1202A-100UG
1 mg
£405.00
E-AB-F1202A-1MG
5 mg
£1515.00
E-AB-F1202A-5MG
25 mg
£5832.00
E-AB-F1202A-25MG
50 mg
£10187.00
E-AB-F1202A-50MG
100 mg
£14542.00
E-AB-F1202A-100MG
About this Product
- SKU:
- E-AB-F1202A
- Additional Names:
- CVID;Interleukin;IL21;CVID11;IL-21;Za11;Interleukin-21
- Application:
- Flow Cytometry
- Buffer:
- PBS, pH 7.2. Contains 0.05% proclin 300.
- translate.label.attr.clone:
- 3A3-N2
- Clonality:
- Monoclonal
- Concentration:
- >= 1 mg/ml
- Extra Details:
- Interleukin-21 (IL-21) is the most recently described cytokine belonging to the common cytokine receptor gamma-chain family. Like other common gamma chain family members, IL-21 is a four alpha-helix bundle type I cytokine. It signals through a receptor complex consisting of IL-21 R and common gamma-chain/IL-2 R gamma. IL-21 is produced primarily by CD4+ T cells and natural killer T (NKT) cells and has a broad range of effects on a number of different cell types. IL-21 signaling in CD4+ T cells is required for both Th17 differentiation and the geneRation of T follicular helper (Tfh) cells, which support B cell differentiation and antibody production in germinal centers. IL-21 also directly regulates B cell prolifeRation and apoptosis in a context-dependent manner and can promote immunoglobulin production and isotype class switching. In addition, IL-21 signaling enhances the cytotoxicity of CD8+ T cells, natural killer cells, and NKT cells.
- Host:
- Mouse
- Immunogen:
- IL-21|Recombinant Human IL-21 protein
- Isotype:
- IgG1, kappa
- Purity:
- >98%
- Purification:
- protein a/g purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:bbNIU5Ru
