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Antibodies

Purified Anti-Human IL-21 Antibody[3A3-N2]

Product Sizes
25 ug
£99.00
E-AB-F1202A-25UG
100 ug
£169.00
E-AB-F1202A-100UG
1 mg
£405.00
E-AB-F1202A-1MG
5 mg
£1515.00
E-AB-F1202A-5MG
25 mg
£5832.00
E-AB-F1202A-25MG
50 mg
£10187.00
E-AB-F1202A-50MG
100 mg
£14542.00
E-AB-F1202A-100MG
About this Product
SKU:
E-AB-F1202A
Additional Names:
CVID;Interleukin;IL21;CVID11;IL-21;Za11;Interleukin-21
Application:
Flow Cytometry
Buffer:
PBS, pH 7.2. Contains 0.05% proclin 300.
translate.label.attr.clone:
3A3-N2
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
Interleukin-21 (IL-21) is the most recently described cytokine belonging to the common cytokine receptor gamma-chain family. Like other common gamma chain family members, IL-21 is a four alpha-helix bundle type I cytokine. It signals through a receptor complex consisting of IL-21 R and common gamma-chain/IL-2 R gamma. IL-21 is produced primarily by CD4+ T cells and natural killer T (NKT) cells and has a broad range of effects on a number of different cell types. IL-21 signaling in CD4+ T cells is required for both Th17 differentiation and the geneRation of T follicular helper (Tfh) cells, which support B cell differentiation and antibody production in germinal centers. IL-21 also directly regulates B cell prolifeRation and apoptosis in a context-dependent manner and can promote immunoglobulin production and isotype class switching. In addition, IL-21 signaling enhances the cytotoxicity of CD8+ T cells, natural killer cells, and NKT cells.
Host:
Mouse
Immunogen:
IL-21|Recombinant Human IL-21 protein
Isotype:
IgG1, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody