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Antibodies

AF/LE Purified Anti-Human CD28 Antibody[CD28.2]

Product Sizes
50 ug
£198.00
E-AB-F11950-50UG
500 ug
£380.00
E-AB-F11950-500UG
1 mg
£594.00
E-AB-F11950-1MG
About this Product
SKU:
E-AB-F11950
Additional Names:
PAS2,MNS,HGpMiX,GYPA,GPSAT
Application:
Activate/Stimulate, Flow Cytometry
Buffer:
0.2 uM PBS
Clone:
CD28.2
Clonality:
Monoclonal
Concentration:
0.5 mg/ml
Extra Details:
CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Host:
Mouse
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody