APC Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]
Product Sizes
50 tests
£81.00
E-AB-F1177E-50TESTS
100 tests
£104.00
E-AB-F1177E-100TESTS
2 x 100 tests
£147.00
E-AB-F1177E-2X100TESTS
About this Product
- SKU:
- E-AB-F1177E
- Additional Names:
- CD 150;Signaling lymphocytic activation molecule;Slam;Slamf1
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- TC15-12F12.2
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 5 ul/test
- Extra Details:
- CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-G Gamma production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.
- Host:
- Rat
- Immunogen:
- CD150/SLAM
- Isotype:
- IgG2a, lambda
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:slam_antibody[tc15_12f12.2]-e_ab_f1177e
