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Antibodies

Purified Anti-Mouse CD150 Antibody[TC15-12F12.2], Functional Grade

Product Sizes
100 ug
£89.00
E-AB-F11770-100UG
1 mg
£171.00
E-AB-F11770-1MG
5 mg
£490.00
E-AB-F11770-5MG
25 mg
£1515.00
E-AB-F11770-25MG
50 mg
£2247.00
E-AB-F11770-50MG
100 mg
£3211.00
E-AB-F11770-100MG
About this Product
SKU:
E-AB-F11770
Additional Names:
SLAM family member,SLAMF,CD 150,CD150,CD150 antigen,Signaling lymphocytic activation molecule,SLAM family member 1,Slam,Slamf1, IPO-3
Application:
Block/Inhibit/Neutralise, Flow Cytometry, Stimulation
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
TC15-12F12.2
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-G Gamma production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Rat
Immunogen:
Recombinant Mouse CD150 protein
Isotype:
IgG2a, lambda
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD150 Antibody[TC15-12F12.2], Functional Grade (Right) and 0.2 ug Rat Ig2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
Human peripheral blood granulocytes were stained with 0.2 ug AF/LE Purified Anti-Human CD11c Antibody[3.9] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD172g Antibody[OX-119] (Rig Monoclonal Antibody[OX-119] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD3 FITC-conjugated Monoclonal Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD52 Antibody[5F7] (Right) and 0.2 ug Mouse IgG3, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood granulocytes were stained with 0.2 ug Purified Anti-Human CD11c Antibody[3.9] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.