APC Anti-Human IL-17A Antibody[BL168]
Product Sizes
20 tests
£225.00
E-AB-F1173E-20TESTS
100 tests
£353.00
E-AB-F1173E-100TESTS
2 x 100 tests
£471.00
E-AB-F1173E-2X100TESTS
About this Product
- SKU:
- E-AB-F1173E
- Additional Names:
- CTLA8, IL17,CTLA-8,IL 17A
- Application:
- Flow Cytometry
- Buffer:
- pbs
- Clone:
- BL168
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-K KappaB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
- Host:
- Mouse
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-apc_anti_human_il_17a_antibody_bl168_e_ab_f1173e-172831.html