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Antibodies

Elab Fluor[R] Violet 610 Anti-Human CD197/CCR7 Antibody[G043H7]

Product Sizes
20 tests
£139.00
E-AB-F1159T-20TESTS
100 tests
£270.00
E-AB-F1159T-100TESTS
2 x 100 tests
£378.00
E-AB-F1159T-2X100TESTS
About this Product
SKU:
E-AB-F1159T
Additional Names:
EBI1EVI1;CCR-7;CDw197;CMKBR7
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
G043H7
Clonality:
Monoclonal
Conjugate:
Elab Fluor® Violet 610
Concentration:
5 ul/test
Extra Details:
CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.
Host:
Mouse
Immunogen:
CD197/CCR7
Isotype:
IgG2a, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Staining of normal human peripheral blood cells with FITC Anti-Human CD3 Antibody and Elab Fluor® Violet 610 Anti-Human CD197/CCR7 Antibody[G043H7](left) or Elab Fluor® Violet 610 Mouse IgG2a, K Kappa Isotype Control (right). Cells in the lymphocytes gate were used for analysis.