APC Anti-Human CD127/IL-7RA Antibody[A019D5]
Product Sizes
20 tests
£230.00
E-AB-F1152E-20TESTS
100 tests
£375.00
E-AB-F1152E-100TESTS
2 x 100 tests
£514.00
E-AB-F1152E-2X100TESTS
About this Product
- SKU:
- E-AB-F1152E
- Additional Names:
- Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7RA Alpha
- Application:
- Flow Cytometry
- Buffer:
- pbs
- Clone:
- A019D5
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor A Alpha chain or IL-7RA Alpha. It forms a heterodimer with the common G Gamma chain (G Gammac or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
- Host:
- Mouse
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-apc_anti_human_cd127_il_7ra_antibody_a019d5_e_ab_f1152e-172773.html