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Antibodies

Biotin Anti-Human CD127/IL-7RA Antibody[A019D5]

Product Sizes
25 ug
£151.00
E-AB-F1152B-25UG
100 ug
£374.00
E-AB-F1152B-100UG
About this Product
SKU:
E-AB-F1152B
Additional Names:
CD127;CDw127;IL-7RA;IL-7RA Alpha;Interleukin-7 receptor subunit alpha
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
A019D5
Clonality:
Monoclonal
Conjugate:
Biotin
Concentration:
0.5 mg/ml
Extra Details:
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor A Alpha chain or IL-7RA Alpha. It forms a heterodimer with the common G Gamma chain (G Gammac or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
Host:
Mouse
Immunogen:
CD127
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Human peripheral blood lymphocytes are stained with FITC Anti-Human CD3 Antibody and Biotin Anti-Human CD127/IL-7RA Antibody followed by Streptavidin-Elab Fluor® 647 (Left). Lymphocytes are stained with FITC Anti-Human CD3 Antibody and Biotin Mouse Rat IgG1, K Kappa Isotype Control followed by with Streptavidin-Elab Fluor® 647 (Right).