Elab Fluor[R] 700 Anti-Human CD107a/LAMP-1 Antibody[H4A3]
Product Sizes
20 tests
£139.00
E-AB-F1149M1-20TESTS
100 tests
£270.00
E-AB-F1149M1-100TESTS
2 x 100 tests
£378.00
E-AB-F1149M1-2X100TESTS
About this Product
- SKU:
- E-AB-F1149M1
- Additional Names:
- LAMP-1; LGP-120;Lysosome-Associated Membrane Protein 1;LAMP-1
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- H4A3
- Clonality:
- Monoclonal
- Conjugate:
- Elab Fluor® 700
- Extra Details:
- CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
- Host:
- Mouse
- Immunogen:
- CD107a/LAMP-1
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:lamp_1_antibody[h4a3]-e_ab_f1149m1
