Elab Fluor[R] 647 Anti-Human CD49d Antibody[9F10]
Product Sizes
20 tests
£131.00
E-AB-F1144M-20TESTS
100 tests
£259.00
E-AB-F1144M-100TESTS
2 x 100 tests
£383.00
E-AB-F1144M-2X100TESTS
About this Product
- SKU:
- E-AB-F1144M
- Additional Names:
- CD49 antigen-like family member D;CD49d;ITGA4;Integrin alpha-4;Integrin alpha-IV;VLA-4 subunit alpha
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 9F10
- Clonality:
- Monoclonal
- Conjugate:
- Elab Fluor® 647
- Concentration:
- 5 ul/test
- Extra Details:
- CD49d is a 150 kD A Alpha integrin chain known as A Alpha4 integrin or VLA-4 A Alpha chain. It forms a heterodimer with either integrin B Beta1 (A Alpha4B Beta1, VLA-4) or B Beta7 (A Alpha4B Beta7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. A Alpha4B Beta7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
- Host:
- Mouse
- Immunogen:
- CD49d
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-elab_fluor®_647_anti_human_cd49d_antibody[9f10]-e_ab_f1144m
