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Antibodies

APC Anti-Human CD45 Antibody[HI30]

Product Sizes
20 tests
£156.00
E-AB-F1137E-20TESTS
100 tests
£214.00
E-AB-F1137E-100TESTS
2 x 100 tests
£263.00
E-AB-F1137E-2X100TESTS
About this Product
SKU:
E-AB-F1137E
Additional Names:
Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45
Application:
Flow Cytometry
Buffer:
pbs
Clone:
HI30
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Host:
Mouse
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody