Biotin Anti-Human CD274/PD-L1 Antibody[29E.2A3]
Product Sizes
25 ug
£95.00
E-AB-F1133B-25UG
100 ug
£161.00
E-AB-F1133B-100UG
About this Product
- SKU:
- E-AB-F1133B
- Additional Names:
- B7H1PD-L1PDCD1L1PDCD1LG1PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 29E.2A3
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-G Gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
- Host:
- Mouse
- Immunogen:
- PD-L1
- Isotype:
- IgG2b, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:pd_l1_antibody[29e.2a3]-e_ab_f1133b
