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Antibodies

Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3]

Product Sizes
25 ug
£66.00
E-AB-F1133A-25UG
100 ug
£89.00
E-AB-F1133A-100UG
1 mg
£165.00
E-AB-F1133A-1MG
5 mg
£467.00
E-AB-F1133A-5MG
25 mg
£1438.00
E-AB-F1133A-25MG
50 mg
£2132.00
E-AB-F1133A-50MG
100 mg
£2980.00
E-AB-F1133A-100MG
About this Product
SKU:
E-AB-F1133A
Additional Names:
B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
Application:
Flow Cytometry
Buffer:
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
translate.label.attr.clone:
29E.2A3
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-G Gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Host:
Mouse
Immunogen:
PD-L1|Recombinant Human PD-L1 protein
Isotype:
IgG2b, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:z5W1CS