AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3]
Product Sizes
25 ug
£66.00
E-AB-F11330-25UG
100 ug
£89.00
E-AB-F11330-100UG
1 mg
£171.00
E-AB-F11330-1MG
5 mg
£490.00
E-AB-F11330-5MG
25 mg
£1515.00
E-AB-F11330-25MG
50 mg
£2247.00
E-AB-F11330-50MG
100 mg
£3211.00
E-AB-F11330-100MG
About this Product
- SKU:
- E-AB-F11330
- Additional Names:
- B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
- Application:
- Flow Cytometry
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- 29E.2A3
- Clonality:
- Monoclonal
- Concentration:
- >= 1 mg/ml
- Extra Details:
- CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-G Gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
- Host:
- Mouse
- Immunogen:
- PD-L1|Recombinant Human PD-L1 protein
- Isotype:
- IgG2b, kappa
- Purity:
- >98%
- Purification:
- protein a/g purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:a18CCG
