AF/LE Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
Product Sizes
50 ug
£198.00
E-AB-F11320-50UG
500 ug
£380.00
E-AB-F11320-500UG
1 mg
£594.00
E-AB-F11320-1MG
About this Product
- SKU:
- E-AB-F11320
- Additional Names:
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- 0.2 uM PBS
- Clone:
- 10F.9G2
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-G Gamma activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-G Gamma, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
- Host:
- Rat
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-af_le_purified_anti_mouse_cd274_pd_l1_antibody_10f.9g2_e_ab_f11320-208960.html