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Antibodies

Purified Anti-Mouse CD279/PD-1 Antibody[29F.1A12], Functional Grade

Product Sizes
100 ug
£89.00
E-AB-F11310-100UG
1 mg
£171.00
E-AB-F11310-1MG
5 mg
£490.00
E-AB-F11310-5MG
25 mg
£1515.00
E-AB-F11310-25MG
50 mg
£2247.00
E-AB-F11310-50MG
100 mg
£3211.00
E-AB-F11310-100MG
About this Product
SKU:
E-AB-F11310
Additional Names:
Programmed Death-1,PD-1
Application:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
29F.1A12
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Rat
Immunogen:
Recombinant Mouse CD279 protein
Isotype:
IgG2a, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody