AF/LE Purified Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Product Sizes
50 ug
£220.00
E-AB-F11310-50UG
500 ug
£541.00
E-AB-F11310-500UG
1 mg
£755.00
E-AB-F11310-1MG
About this Product
- SKU:
- E-AB-F11310
- Additional Names:
- PD-1, Programmed Death-1
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- 0.2 uM PBS
- Clone:
- 29F.1A12
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
- Host:
- Rat
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-af_le_purified_anti_mouse_cd279_pd_1_antibody_29f.1a12_e_ab_f11310-176605.html