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Antibodies

Purified Anti-Human CD279/PD-1 Antibody[J116]

Product Sizes
25 ug
£66.00
E-AB-F1129A-25UG
100 ug
£89.00
E-AB-F1129A-100UG
1 mg
£165.00
E-AB-F1129A-1MG
5 mg
£467.00
E-AB-F1129A-5MG
25 mg
£1438.00
E-AB-F1129A-25MG
50 mg
£2132.00
E-AB-F1129A-50MG
100 mg
£2980.00
E-AB-F1129A-100MG
About this Product
SKU:
E-AB-F1129A
Additional Names:
Programmed Death-1;PD-1
Application:
Flow Cytometry
Buffer:
PBS, pH 7.2. Contains 0.05% proclin 300.
translate.label.attr.clone:
J116
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
Host:
Mouse
Immunogen:
CD279|Recombinant Human CD279 protein
Isotype:
IgG1, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:vz5K8G
C57/BL6 Mouse splenocytes were stained with 0.2 ug AF/LE Purified Anti-Mouse CD16/32 Antibody[2.4G2] (Right) and 0.2 ug Rat IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti- Rat IgG Secondary Antibody, then anti-Mouse B220 PE-conjugated Monoclonal Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug AF/LE Purified Anti-Mouse CD62L Antibody[MEL-14] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Rat IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD19 Antibody[CB19] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD22 PE-conjugated Monoclonal Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD3 Antibody[OKT-3](Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control(Left), followed by PE-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug AF/LE Purified Anti-Human CD3 Antibody[OKT-3] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by PE-conjugated Goat Anti-Mouse IgG Secondary Antibody.