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Antibodies

Purified Anti-Mouse TCR G Gamma/D Delta Antibody[UC7-13D5], Functional Grade

Product Sizes
100 ug
£89.00
E-AB-F11240-100UG
1 mg
£171.00
E-AB-F11240-1MG
5 mg
£490.00
E-AB-F11240-5MG
25 mg
£1515.00
E-AB-F11240-25MG
50 mg
£2247.00
E-AB-F11240-50MG
100 mg
£3211.00
E-AB-F11240-100MG
About this Product
SKU:
E-AB-F11240
Additional Names:
G Gamma/D Delta TCR,TCR-G Gamma/D Delta
Application:
Block/Inhibit/Neutralise, Flow Cytometry, Stimulation
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
UC7-13D5
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
T cell receptor (TCR) is a heterodimer consisting of an A Alpha and a B Beta chain (TCR A Alpha/B Beta) or a G Gamma and a D Delta chain (TCR G Gamma/D Delta). TCR G Gamma/D Delta belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR G Gamma/D Delta associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most G Gamma/D Delta T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR G Gamma/D Delta have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that G Gamma/D Delta T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-G Gamma/D Delta-bearing T cells in vitro, and to deplete peripheral TCR-G Gamma/D Delta-bearing T cells in vivo. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Hamster
Immunogen:
TCR γ/δ
Isotype:
IgG
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
HEK293T cells transfected with pcDNA3.1 plasmid encoding Human CD137 gene were stained with 0.2 ug Purified Anti-Human CD137 Antibody[BBK-2] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes cell were stained with 0.2 ug Purified Anti-Human CD268 Antibody[6G10] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD19 PE-conjugated Monoclonal Antibody.
HEK293T cells transfected with pcDNA3.1 plasmid encoding Human LOX-1 gene were stained with 0.2 ug Purified Anti-Human LOX-1 Antibody[15C4] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
HEK293T cells transfected with pcDNA3.1 plasmid encoding Human CD137 gene were stained with 0.2 ug Purified Anti-Human CD137 Antibody[BBK-2] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.