Biotin Anti-Mouse CD119 Antibody[GR-20]
Product Sizes
25 ug
£78.00
E-AB-F1115B-25UG
100 ug
£114.00
E-AB-F1115B-100UG
About this Product
- SKU:
- E-AB-F1115B
- Additional Names:
- CD119;IFN-gamma-R-alpha;IFN-gamma-R1;Ifngr1;Interferon gamma receptor 1
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- GR-20
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-G GammaRA Alpha chain. It is a class II cytokine receptor family member that serves as a IFN-G Gamma-binding chain associated with the IFN-G Gamma B Beta chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-G Gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-G Gamma initiates and regulates a variety of immune responses.
- Host:
- Rat
- Immunogen:
- CD119
- Isotype:
- IgG2a, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-biotin_anti_mouse_cd119_antibody[gr_20]-e_ab_f1115b
