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Antibodies

APC Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]

Product Sizes
50 tests
£81.00
E-AB-F1112E-50TESTS
100 tests
£104.00
E-AB-F1112E-100TESTS
2 x 100 tests
£147.00
E-AB-F1112E-2X100TESTS
About this Product
SKU:
E-AB-F1112E
Additional Names:
B220
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
RA3.3A 1/6.1
Clonality:
Monoclonal
Conjugate:
APC
Concentration:
5 ul/test
Extra Details:
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Host:
Rat
Immunogen:
CD45R/B220
Isotype:
IgM, kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody