Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Elab Fluor[R] 647 Anti-Human CD8a Antibody[OKT-8]

Product Sizes
20 tests
£98.00
E-AB-F1110M-20TESTS
100 tests
£171.00
E-AB-F1110M-100TESTS
2 x 100 tests
£235.00
E-AB-F1110M-2X100TESTS
About this Product
SKU:
E-AB-F1110M
Additional Names:
CD8A;MAL;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
OKT-8
Clonality:
Monoclonal
Conjugate:
Elab Fluor® 647
Concentration:
5 ul/test
Extra Details:
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the A Alpha3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Host:
Mouse
Immunogen:
CD8
Isotype:
IgG2a, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:y1eXLK