Biotin Anti-Human CD8a Antibody[OKT-8]
Product Sizes
25 ug
£74.00
E-AB-F1110B-25UG
100 ug
£114.00
E-AB-F1110B-100UG
About this Product
- SKU:
- E-AB-F1110B
- Additional Names:
- CD8A;MAL;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- OKT-8
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the A Alpha3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
- Host:
- Mouse
- Immunogen:
- CD8
- Isotype:
- IgG2a, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:bj1qr1
