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Antibodies

Purified Anti-Human CD8a Antibody[OKT-8], Functional Grade

Product Sizes
100 ug
£89.00
E-AB-F11100-100UG
1 mg
£171.00
E-AB-F11100-1MG
5 mg
£490.00
E-AB-F11100-5MG
25 mg
£1515.00
E-AB-F11100-25MG
50 mg
£2247.00
E-AB-F11100-50MG
100 mg
£3211.00
E-AB-F11100-100MG
About this Product
SKU:
E-AB-F11100
Additional Names:
CD8A,MAL,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2
Application:
Depletion, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
OKT-8
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the A Alpha3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Mouse
Immunogen:
Recombinant Human CD8 protein
Isotype:
IgG2a, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD8a Antibody[OKT-8], Functional Grade (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse CD107a gene were stained with 0.2 ug Purified Anti-Mouse CD107a Antibody[1D4B] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD73 Antibody[AD2] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by APC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood granulocytes cell were stained with 0.2 ug Purified Anti-Human CD66b Antibody[G10F5] (Right) and 0.2 ug Mouse IgM, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgM Secondary Antibody
Human peripheral blood granulocytes cell were stained with 0.2 ug Purified Anti-Human CD33 Antibody[WM53] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.