Purified Anti-Rat Cd8a Antibody[OX-8], Functional Grade
Product Sizes
100 ug
£89.00
E-AB-F10980-100UG
1 mg
£171.00
E-AB-F10980-1MG
5 mg
£490.00
E-AB-F10980-5MG
25 mg
£1515.00
E-AB-F10980-25MG
50 mg
£2247.00
E-AB-F10980-50MG
100 mg
£3211.00
E-AB-F10980-100MG
About this Product
- SKU:
- E-AB-F10980
- Additional Names:
- T-lymphocyte differentiation antigen T8/Leu,MAL,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2,Cd8a
- Application:
- Depletion, Flow Cytometry
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- OX-8
- Clonality:
- Monoclonal
- Concentration:
- >= 1 mg/ml
- Extra Details:
- CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked A Alpha and B Beta chains that form the A Alpha(CD8a)/B Beta(CD8b) heterodimer and A Alpha/A Alpha homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 A Alpha/B Beta heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR A Alpha/B Beta T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 A Alpha/A Alpha homodimer is expressed on a subset of G Gamma/D Delta TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Host:
- Mouse
- Immunogen:
- Recombinant Rat CD8a protein
- Isotype:
- IgG1, kappa
- Purification:
- protein a/g purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-purified_anti_rat_cd8a_antibody[ox_8],_functional_grade-e_ab_f10980
