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Antibodies

Elab Fluor[R] 488 Anti-Human CD47 Antibody[CC2C6D4]

Product Sizes
20 tests
£120.00
E-AB-F1060L-20TESTS
100 tests
£197.00
E-AB-F1060L-100TESTS
2 x 100 tests
£270.00
E-AB-F1060L-2X100TESTS
About this Product
SKU:
E-AB-F1060L
Additional Names:
Cd47;IAP;Integrin-associated protein;Leukocyte surface antigen CD47
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
CC2C6D4
Clonality:
Monoclonal
Conjugate:
Elab Fluor® 488
Concentration:
5 ul/test
Extra Details:
CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with B Beta3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and B Beta3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
Host:
Mouse
Immunogen:
CD47
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody