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Antibodies

APC Anti-Human CD47 Antibody[CC2C6D4]

Product Sizes
20 tests
£214.00
E-AB-F1060E-20TESTS
100 tests
£353.00
E-AB-F1060E-100TESTS
2 x 100 tests
£471.00
E-AB-F1060E-2X100TESTS
About this Product
SKU:
E-AB-F1060E
Additional Names:
Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Application:
Flow Cytometry
Buffer:
pbs
Clone:
CC2C6D4
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with B Beta3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and B Beta3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
Host:
Mouse
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody