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Antibodies

Elab Fluor[R] 700 Anti-Human CD40 Antibody[3A8]

Product Sizes
20 tests
£128.00
E-AB-F1037M1-20TESTS
100 tests
£251.00
E-AB-F1037M1-100TESTS
2 x 100 tests
£351.00
E-AB-F1037M1-2X100TESTS
About this Product
SKU:
E-AB-F1037M1
Additional Names:
B-cell surface antigen CD40;Bp50;CD40;CD40L receptor;Cd40;Tnfrsf5;Tumor necrosis factor receptor superfamily member 5
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
3A8
Clonality:
Monoclonal
Conjugate:
Elab Fluor® 700
Extra Details:
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
Host:
Mouse
Immunogen:
CD40
Isotype:
IgG2a, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody