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Antibodies

Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45], Functional Grade

Product Sizes
100 ug
£89.00
E-AB-F10280-100UG
1 mg
£171.00
E-AB-F10280-1MG
5 mg
£490.00
E-AB-F10280-5MG
25 mg
£1515.00
E-AB-F10280-25MG
50 mg
£2247.00
E-AB-F10280-50MG
100 mg
£3211.00
E-AB-F10280-100MG
About this Product
SKU:
E-AB-F10280
Additional Names:
B-cell surface antigen CD40,Bp50,CD40,CD40L receptor,Cd40,Tnfrsf5,Tumor necrosis factor receptor superfamily member 5
Application:
Activate/Stimulate, Flow Cytometry, Stimulation
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
FGK4.5/FGK45
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Rat
Immunogen:
Recombinant Mouse CD40 protein
Isotype:
IgG2a, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45], Functional Grade (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse CD3 PE-conjugated Monoclonal Antibody.
HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse CD279 gene were stained with 0.2 ug AF/LE Purified Anti-Mouse CD279 Antibody[29F.1A12] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor®647-conjugated Goat Anti-Rat IgG Secondary Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug AF/LE Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] (Right) and 0.2 ug Rat IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
Human peripheral blood lymphocytes were activated for 3 days with PHA, then stained with 0.2 ug AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3] (Right) and 0.2 ug Mouse IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD3 PE-conjugated Monoclonal Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human HLA-A,B,C Antibody[W6/32](Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control(Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.