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Antibodies

Purified Anti-Mouse CD127/IL-7RA Antibody[A7R34], Functional Grade

Product Sizes
100 ug
£89.00
E-AB-F10230-100UG
1 mg
£171.00
E-AB-F10230-1MG
5 mg
£490.00
E-AB-F10230-5MG
25 mg
£1515.00
E-AB-F10230-25MG
50 mg
£2247.00
E-AB-F10230-50MG
100 mg
£3211.00
E-AB-F10230-100MG
About this Product
SKU:
E-AB-F10230
Additional Names:
CD127,IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7RA,IL-7Ralpha,IL-7R-alpha,Interleukin-7 receptor subunit alpha,Il7r
Application:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
A7R34
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor A Alpha chain or IL-7RA Alpha. It forms a heterodimer with the common G Gamma chain (G Gammac or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Rat
Immunogen:
Recombinant Mouse CD127/IL-7RA protein
Isotype:
IgG2a, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD127/IL-7RA Antibody[A7R34], Functional Grade (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse CD3 PE-conjugated Monoclonal Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD4 Antibody[RPA-T4](Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control(Left), followed by PE-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug AF/LE Purified Anti-Human CD4 Antibody[RPA-T4] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by PE-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Rat splenocytes were stained with 0.2 ug Purified Anti-Rat CD4(domain 1) Antibody[OX-38] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Mouse peritoneal macrophages were stained with 0.2 ug AF/LE Purified Anti-Mouse CD115 Antibody[AFS98](Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control(Left), followed by APC-conjugated Goat Anti-Rat IgG Secondary Antibody.