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Antibodies

Purified Anti-Mouse CD22 Antibody[Cy34.1]

Product Sizes
25 ug
£66.00
E-AB-F1021A-25UG
100 ug
£89.00
E-AB-F1021A-100UG
1 mg
£165.00
E-AB-F1021A-1MG
5 mg
£467.00
E-AB-F1021A-5MG
25 mg
£1438.00
E-AB-F1021A-25MG
50 mg
£2132.00
E-AB-F1021A-50MG
100 mg
£2980.00
E-AB-F1021A-100MG
About this Product
SKU:
E-AB-F1021A
Additional Names:
Lyb;SIGLEC2FLJ;B-cell receptor CD;T-cell surface antigen Leu;sialic acid binding Ig-like lectin;Sialic acid-binding Ig-like lectin;B-cell receptor CD22;BL-CAM;B-lymphocyte cell adhesion molecule;CD22 antigenMGC130020;CD22 molecule;sialic acid binding Ig-like lectin 2;Sialic acid-binding Ig-like lectin 2;Siglec-2;SIGLEC2FLJ22814;T-cell surface antigen Leu-14;Lyb-8;Siglec2;Cd22;Lyb8;Siglec-2
Application:
Flow Cytometry
Buffer:
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
translate.label.attr.clone:
Cy34.1
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig u chain are augmented in the presence of Cy34.1 mAb.
Host:
Mouse
Immunogen:
CD22
Isotype:
IgG1, kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:OqrTC8
C57/BL6 Mouse bone marrow cells were stained with 0.2 ug Purified Anti-Mouse CD71 Antibody[R17 217.1.3/TIB-219](Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control(Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse Ter-119 PE-conjugated Monoclonal Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug AF/LE Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] (Right) and 0.2 ug Rat IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse CD3e FITC-conjugated Monoclonal Antibody.
C57/BL6 Mouse bone marrow cells were stained with 0.2 ug AF/LE Purified Anti-Mouse CD71 Antibody[R17 217.1.3/TIB-219] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse Ter-119 PE-conjugated Monoclonal Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12](Right) and 0.2 ug Rat IgG2b, K Kappa Isotype Control(Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse CD3e FITC-conjugated Monoclonal Antibody.