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Antibodies

Biotin Anti-Human CD86 Antibody[BU63]

Product Sizes
25 ug
£104.00
E-AB-F1012B-25UG
100 ug
£205.00
E-AB-F1012B-100UG
About this Product
SKU:
E-AB-F1012B
Additional Names:
Activation B7-2 antigen;Cd86;ETC-1;Early T-cell costimulatory molecule 1;T-lymphocyte activation antigen CD86
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
BU63
Clonality:
Monoclonal
Conjugate:
Biotin
Concentration:
0.5 mg/ml
Extra Details:
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Host:
Mouse
Immunogen:
CD86
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody